LC-MS-based identification of bioactive compounds and hepatoprotective and nephroprotective activities of <i>Bignonia binata</i> leaves against carbon tetrachloride-induced injury in rats.

Samy, Mamdouh Nabil; Hamed, Ashraf Nageeb Elsayed; Mahmoud, Basma Khalaf; Attia, Eman Zekry; Abdelmohsen, Usama Ramadan; Fawzy, Michael Atef; Attya, Mina Ezzat; Kamel, Mohamed Salah

LC-MS-based identification of bioactive compounds and hepatoprotective and nephroprotective activities of Bignonia binata leaves against carbon tetrachloride-induced injury in rats.

Samy, Mamdouh Nabil; Hamed, Ashraf Nageeb Elsayed; Mahmoud, Basma Khalaf; Attia, Eman Zekry; Abdelmohsen, Usama Ramadan; Fawzy, Michael Atef; Attya, Mina Ezzat; Kamel, Mohamed Salah.

Afiliação

Samy MN; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Hamed ANE; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Mahmoud BK; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Attia EZ; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Abdelmohsen UR; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Fawzy MA; Department of Botany II, Julius-von-Sachs Institute for Biological Sciences, University of Würzburg, Würzburg, Germany.
Attya ME; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia City, Egypt.
Kamel MS; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.

Nat Prod Res ; 36(5): 1375-1379, 2022 Mar.

Article em En | MEDLINE | ID: mdl-33487045

Assuntos

Tetracloreto de Carbono; Doença Hepática Induzida por Substâncias e Drogas; Animais; Antioxidantes/farmacologia; Doença Hepática Induzida por Substâncias e Drogas/tratamento farmacológico; Doença Hepática Induzida por Substâncias e Drogas/prevenção & controle; Cromatografia Líquida; Fígado/metabolismo; Extratos Vegetais/química; Folhas de Planta/química; Ratos; Espectrometria de Massas em Tandem

Palavras-chave

Bignonia binata; carbon tetrachloride; flavonoids; hepatoprotective; metabolomics profiling; nephroprotective; phenolics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tetracloreto de Carbono / Doença Hepática Induzida por Substâncias e Drogas Tipo de estudo: Diagnostic_studies Idioma: En Revista: Nat Prod Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito

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