Dietary Supplementation with Exogenous Sea-Cucumber-Derived Ceramides and Glucosylceramides Alleviates Insulin Resistance in High-Fructose-Diet-Fed Rats by Upregulating the IRS/PI3K/Akt Signaling Pathway.

Yang, Jin-Yue; Zhang, Tian-Tian; Dong, Zhe; Shi, Hao-Hao; Xu, Jie; Mao, Xiang-Zhao; Wang, Yu-Ming; Xue, Chang-Hu

Yang, Jin-Yue; Zhang, Tian-Tian; Dong, Zhe; Shi, Hao-Hao; Xu, Jie; Mao, Xiang-Zhao; Wang, Yu-Ming; Xue, Chang-Hu.

Afiliação

Yang JY; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.
Zhang TT; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.
Dong Z; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.
Shi HH; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.
Xu J; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.
Mao XZ; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.
Wang YM; Laboratory of Marine Drugs & Biological Products, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao, Shandong 266237, People's Republic of China.
Xue CH; College of Food Science and Engineering, Ocean University of China, Qingdao, Shandong 266003, People's Republic of China.

J Agric Food Chem ; 69(32): 9178-9187, 2021 Aug 18.

Article em En | MEDLINE | ID: mdl-33560835

Assuntos

Cucumis sativus; Resistência à Insulina; Pepinos-do-Mar; Animais; Ceramidas; Cucumis sativus/metabolismo; Dieta; Suplementos Nutricionais; Frutose/efeitos adversos; Glucosilceramidas; Insulina; Masculino; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/genética; Proteínas Proto-Oncogênicas c-akt/metabolismo; Ratos; Ratos Sprague-Dawley; Pepinos-do-Mar/metabolismo; Transdução de Sinais

Palavras-chave

ceramides; glucosylceramides; inflammation; insulin resistance; sea cucumber

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pepinos-do-Mar / Resistência à Insulina / Cucumis sativus Idioma: En Revista: J Agric Food Chem Ano de publicação: 2021 Tipo de documento: Article

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