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Sanhuang Jiangtang tablet protects type 2 diabetes osteoporosis via AKT-GSK3ß-NFATc1 signaling pathway by integrating bioinformatics analysis and experimental validation.
He, Qi; Yang, Junzheng; Zhang, Gangyu; Chen, Delong; Zhang, Meng; Pan, Zhaofeng; Wang, Zihao; Su, Lijun; Zeng, Jiaxu; Wang, Baohua; Wang, Haibin; Chen, Peng.
Afiliação
  • He Q; 1(st) School of Medicine, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzhou, 510405, PR China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China.
  • Yang J; 1(st) School of Medicine, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzhou, 510405, PR China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China.
  • Zhang G; 1(st) School of Medicine, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzhou, 510405, PR China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China.
  • Chen D; Department of Orthopaedic Surgery, Clifford Hospital, Jinan University, Guangzhou, 510006, PR China.
  • Zhang M; Department of Orthopedics, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, Henan, 450003, PR China.
  • Pan Z; 1(st) School of Medicine, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzhou, 510405, PR China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China.
  • Wang Z; Queen's University Belfast, University Road, Belfast, Northen Ireland, BT7 1NN, United Kingdom.
  • Su L; 1(st) School of Medicine, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzhou, 510405, PR China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China.
  • Zeng J; 1(st) School of Medicine, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzhou, 510405, PR China; The Laboratory of Orthopaedics and Traumatology of Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China.
  • Wang B; Department of Endocrinology, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, 510405, PR China. Electronic address: wangbaohua@gzhtcm.edu.cn.
  • Wang H; Department of Orthopaedics, First Affiliated Hospital, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzho, 510405, PR China. Electronic address: hipknee@163.com.
  • Chen P; Department of Orthopaedics, First Affiliated Hospital, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun Area, Guangzho, 510405, PR China. Electronic address: docchen777@gmail.com.
J Ethnopharmacol ; 273: 113946, 2021 Jun 12.
Article em En | MEDLINE | ID: mdl-33647426
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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Osteoporose / Medicamentos de Ervas Chinesas / Transdução de Sinais / Diabetes Mellitus Tipo 2 / Proteínas Proto-Oncogênicas c-akt / Fatores de Transcrição NFATC / Glicogênio Sintase Quinase 3 beta Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Osteoporose / Medicamentos de Ervas Chinesas / Transdução de Sinais / Diabetes Mellitus Tipo 2 / Proteínas Proto-Oncogênicas c-akt / Fatores de Transcrição NFATC / Glicogênio Sintase Quinase 3 beta Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2021 Tipo de documento: Article