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Neurogenic fever due to injury of the hypothalamus in a stroke patient: Case report.
Jang, Sung Ho; Seo, You Sung.
Afiliação
  • Jang SH; Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Namku, Taegu, Republic of Korea.
Medicine (Baltimore) ; 100(13): e24053, 2021 Apr 02.
Article em En | MEDLINE | ID: mdl-33787568
ABSTRACT
RATIONALE Neurogenic fever is a non-infectious source of fever in a patient with brain injury, especially hypothalamic injury. We report on a stroke patient with neurogenic fever due to injury of hypothalamus, demonstrated by using diffusion tensor imaging (DTI). PATIENT CONCERNS A 28-year-old male patient was admitted to the rehabilitation department of university hospital at 30 months after onset. Brain MRI showed leukomalactic lesions in hypothalamus, bilateral medial temporal lobe, and bilateral basal ganglia. He showed intermittent high body temperature (maximum39.5°C, range38.5-39.2°C), but did not show any infection signs upon physical examination or after assessing his white blood cell count and inflammatory enzyme levels such as erythrocyte sedimentation rate and C-reactive protein. In addition, 8 age-matched normal (control) subjects (4 male, mean age 26.6 years, range 21-29years) were enrolled in the study. DIAGNOSIS Intraventricular hemorrhage and intracerebral hemorrhage in the left basal ganglia.

INTERVENTIONS:

He underwent extraventricular drainage and ventriculoperitoneal shunting for hydrocephalus.

OUTCOMES:

DTI was performed at 30 months after onset, fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values were obtained for hypothalamus. The FA and ADC values of patient were lower and higher, respectively, by more than two standard deviations from control values. Injury of hypothalamus was demonstrated in a stroke patient with neurogenic fever. LESSIONS Our results suggest that evaluation of hypothalamus using DTI would be helpful in patients show unexplained fever following brain injury.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Cerebral / Acidente Vascular Cerebral / Febre / Hipotálamo Idioma: En Revista: Medicine (Baltimore) Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Cerebral / Acidente Vascular Cerebral / Febre / Hipotálamo Idioma: En Revista: Medicine (Baltimore) Ano de publicação: 2021 Tipo de documento: Article