Supplementation with Octacosanol Affects the Level of PCSK9 and Restore Its Physiologic Relation with LDL-C in Patients on Chronic Statin Therapy.

Ciric, Milica Zrnic; Ostojic, Miodrag; Baralic, Ivana; Kotur-Stevuljevic, Jelena; Djordjevic, Brizita I; Markovic, Stana; Zivkovic, Stefan; Stankovic, Ivan

Ciric, Milica Zrnic; Ostojic, Miodrag; Baralic, Ivana; Kotur-Stevuljevic, Jelena; Djordjevic, Brizita I; Markovic, Stana; Zivkovic, Stefan; Stankovic, Ivan.

Afiliação

Ciric MZ; Department of Bromatology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Ostojic M; Faculty of Medicine, University of Belgrade, 6 Dr Subotica Street, 11000 Belgrade, Serbia.
Baralic I; Institute for Cardiovascular Diseases "Dedinje", Milana Tepica 1, 11000 Belgrade, Serbia.
Kotur-Stevuljevic J; Department of Cardiology, University Clinical Centre of the Republic of Srpska, 78000 Banja Luka, Bosnia and Herzegovina.
Djordjevic BI; Medical Faculty, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.
Markovic S; Department of Pharmacy, Zvezdara University Medical Center, Dimitrija Tucovica 161, 11000 Belgrade, Serbia.
Zivkovic S; Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Stankovic I; Department of Bromatology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.

Nutrients ; 13(3)2021 Mar 10.

Article em En | MEDLINE | ID: mdl-33802219

Assuntos

LDL-Colesterol/sangue; Suplementos Nutricionais; Álcoois Graxos/administração & dosagem; Pró-Proteína Convertase 9/sangue; Adulto; Idoso; Idoso de 80 Anos ou mais; Anticolesterolemiantes/uso terapêutico; Atorvastatina/uso terapêutico; Método Duplo-Cego; Dislipidemias/tratamento farmacológico; Feminino; Humanos; Hipercolesterolemia/sangue; Hipercolesterolemia/tratamento farmacológico; Masculino; Pessoa de Meia-Idade; Vitamina K 2/administração & dosagem; Vitaminas/administração & dosagem

Palavras-chave

LDL-C; Octacosanol; PCSK9; statins; supplementation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Suplementos Nutricionais / Álcoois Graxos / Pró-Proteína Convertase 9 / LDL-Colesterol Tipo de estudo: Clinical_trials / Risk_factors_studies Idioma: En Revista: Nutrients Ano de publicação: 2021 Tipo de documento: Article

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