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Meningeal lymphatics affect microglia responses and anti-Aß immunotherapy.
Da Mesquita, Sandro; Papadopoulos, Zachary; Dykstra, Taitea; Brase, Logan; Farias, Fabiana Geraldo; Wall, Morgan; Jiang, Hong; Kodira, Chinnappa Dilip; de Lima, Kalil Alves; Herz, Jasmin; Louveau, Antoine; Goldman, Dylan H; Salvador, Andrea Francesca; Onengut-Gumuscu, Suna; Farber, Emily; Dabhi, Nisha; Kennedy, Tatiana; Milam, Mary Grace; Baker, Wendy; Smirnov, Igor; Rich, Stephen S; Benitez, Bruno A; Karch, Celeste M; Perrin, Richard J; Farlow, Martin; Chhatwal, Jasmeer P; Holtzman, David M; Cruchaga, Carlos; Harari, Oscar; Kipnis, Jonathan.
Afiliação
  • Da Mesquita S; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA. damesquita@mayo.edu.
  • Papadopoulos Z; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. damesquita@mayo.edu.
  • Dykstra T; Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, St. Louis, MO, USA.
  • Brase L; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • Farias FG; Neuroscience Graduate Program, Washington University in St. Louis, St. Louis, MO, USA.
  • Wall M; Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, St. Louis, MO, USA.
  • Jiang H; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • Kodira CD; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
  • de Lima KA; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.
  • Herz J; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
  • Louveau A; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Goldman DH; PureTech Health, Boston, MA, USA.
  • Salvador AF; Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, St. Louis, MO, USA.
  • Onengut-Gumuscu S; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • Farber E; Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, St. Louis, MO, USA.
  • Dabhi N; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • Kennedy T; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
  • Milam MG; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
  • Baker W; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
  • Smirnov I; Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, St. Louis, MO, USA.
  • Rich SS; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • Benitez BA; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
  • Karch CM; Center for Brain Immunology and Glia (BIG), Washington University in St. Louis, St. Louis, MO, USA.
  • Perrin RJ; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • Farlow M; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA.
  • Chhatwal JP; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
  • Holtzman DM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
  • Cruchaga C; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
  • Harari O; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
  • Kipnis J; Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.
Nature ; 593(7858): 255-260, 2021 05.
Article em En | MEDLINE | ID: mdl-33911285
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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_manuales / Drenaje_linftico Assunto principal: Peptídeos beta-Amiloides / Microglia / Vasos Linfáticos / Doença de Alzheimer / Anticorpos Monoclonais Humanizados / Imunoterapia / Meninges Tipo de estudo: Prognostic_studies Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Terapias_manuales / Drenaje_linftico Assunto principal: Peptídeos beta-Amiloides / Microglia / Vasos Linfáticos / Doença de Alzheimer / Anticorpos Monoclonais Humanizados / Imunoterapia / Meninges Tipo de estudo: Prognostic_studies Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos