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Modelling the Cost-Effectiveness of Implementing a Dietary Intervention in Renal Transplant Recipients.
Coerts, Friso B; Gout-Zwart, Judith J; Gruppen, Eke G; van der Veen, Yvonne; Postma, Maarten J; Bakker, Stephan J L.
Afiliação
  • Coerts FB; Department of Health Sciences, University Medical Center Groningen (UMCG), University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Gout-Zwart JJ; Department of Nephrology, University Medical Center Groningen (UMCG), University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Gruppen EG; Asc Academics, Professor Enno Dirk Wiersmastraat 5, 9713 GH Groningen, The Netherlands.
  • van der Veen Y; Department of Nephrology, University Medical Center Groningen (UMCG), University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Postma MJ; Department of Nephrology, University Medical Center Groningen (UMCG), University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
  • Bakker SJL; Department of Health Sciences, University Medical Center Groningen (UMCG), University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Nutrients ; 13(4)2021 Apr 02.
Article em En | MEDLINE | ID: mdl-33918259
BACKGROUND: The Dietary Approach to Stop Hypertension (DASH) and potassium supplementation have been shown to reduce the risk of death with a functioning graft (DWFG) and renal graft failure in renal transplant recipients (RTR). Unfortunately, a key problem for patients is the adherence to these diets. The aim of this study is to evaluate the cost-effectiveness and budget impact of higher adherence to either the DASH or potassium supplementation. METHODS: A Markov model was used to simulate the life course of 1000 RTR in the Netherlands. A societal perspective with a lifetime time horizon was used. The potential effect of improvement of dietary adherence was modelled in different scenarios. The primary outcomes are the incremental cost-effectiveness ratio (ICER) and the budget impact. RESULTS: In the base case, improved adherence to the DASH diet saved 27,934,786 and gained 1880 quality-adjusted life years (QALYs). Improved adherence to potassium supplementation saved €1,217,803 and gained 2901 QALYs. Both resulted in dominant ICERs. The budget impact over a five-year period for the entire Dutch RTR population was €8,144,693. CONCLUSION: Improving dietary adherence in RTR is likely to be cost-saving and highly likely to be cost-effective compared to the current standard of care in the Netherlands.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Rim / Potássio na Dieta / Suplementos Nutricionais / Dietoterapia / Abordagens Dietéticas para Conter a Hipertensão Tipo de estudo: Evaluation_studies / Health_economic_evaluation País/Região como assunto: Europa Idioma: En Revista: Nutrients Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Rim / Potássio na Dieta / Suplementos Nutricionais / Dietoterapia / Abordagens Dietéticas para Conter a Hipertensão Tipo de estudo: Evaluation_studies / Health_economic_evaluation País/Região como assunto: Europa Idioma: En Revista: Nutrients Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda