Computational investigation of phytochemicals from <i>Withania somnifera</i> (Indian ginseng/ashwagandha) as plausible inhibitors of GluN2B-containing NMDA receptors.

Ahmad, Iqrar; Kumar, Dileep; Patel, Harun

Computational investigation of phytochemicals from Withania somnifera (Indian ginseng/ashwagandha) as plausible inhibitors of GluN2B-containing NMDA receptors.

Ahmad, Iqrar; Kumar, Dileep; Patel, Harun.

Afiliação

Ahmad I; Division of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, India.
Kumar D; Poona College of Pharmacy, Bharti Vidyapeeth University, Pune, India.
Patel H; Division of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, India.

J Biomol Struct Dyn ; 40(17): 7991-8003, 2022 10.

Article em En | MEDLINE | ID: mdl-33970806

Assuntos

Doenças Neurodegenerativas; Nootrópicos; Panax; Withania; Aminoácidos; Ácido Clorogênico; Humanos; Ligantes; Simulação de Acoplamento Molecular; Doenças Neurodegenerativas/tratamento farmacológico; Compostos Fitoquímicos/farmacologia; Extratos Vegetais; Receptores de N-Metil-D-Aspartato; Withania/química

Palavras-chave

Alzheimer's disease; GluN2B; MMGBSA; NMDA; Withania somnifera; docking; molecular dynamic simulation

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nootrópicos / Doenças Neurodegenerativas / Withania / Panax Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biomol Struct Dyn Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google