PolyTLR7/8a-conjugated, antigen-trapping gold nanorods elicit anticancer immunity against abscopal tumors by photothermal therapy-induced in situ vaccination.

Liu, Xiang; Su, Qi; Song, Huijuan; Shi, Xiaoguang; Zhang, Yuming; Zhang, Chuangnian; Huang, Pingsheng; Dong, Anjie; Kong, Deling; Wang, Weiwei

Liu, Xiang; Su, Qi; Song, Huijuan; Shi, Xiaoguang; Zhang, Yuming; Zhang, Chuangnian; Huang, Pingsheng; Dong, Anjie; Kong, Deling; Wang, Weiwei.

Afiliação

Liu X; Department of Polymer Science and Engineering, Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China; Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300072,
Su Q; Department of Polymer Science and Engineering, Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China; Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300072,
Song H; Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Shi X; Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology and Institute of Polymer Chemistry, College of Chemistry, Nankai University, Tianjin, 300071, China.
Zhang Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China. Electronic address: zhangyumin21@163.com.
Zhang C; Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Huang P; Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China.
Dong A; Department of Polymer Science and Engineering, Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China; Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300072,
Kong D; State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, China.
Wang W; Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China. Electronic address: wwwangtj@163.com.

Biomaterials ; 275: 120921, 2021 08.

Article em En | MEDLINE | ID: mdl-34139508

Assuntos

Nanotubos; Neoplasias; Animais; Linhagem Celular Tumoral; Ouro; Camundongos; Neoplasias/terapia; Fototerapia; Terapia Fototérmica; Vacinação

Palavras-chave

Antitumor immunity; Cancer immunotherapy; Gold nanorods; Photothermal therapy; Vaccination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanotubos / Neoplasias Idioma: En Revista: Biomaterials Ano de publicação: 2021 Tipo de documento: Article