Your browser doesn't support javascript.
loading
Silver Nanoparticles Using Eucalyptus or Willow Extracts (AgNPs) as Contact Lens Hydrogel Components to Reduce the Risk of Microbial Infection.
Rossos, Andreas K; Banti, Christina N; Raptis, Panagiotis K; Papachristodoulou, Christina; Sainis, Ioannis; Zoumpoulakis, Panagiotis; Mavromoustakos, Thomas; Hadjikakou, Sotiris K.
Afiliação
  • Rossos AK; Section of Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
  • Banti CN; Section of Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
  • Raptis PK; Section of Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
  • Papachristodoulou C; Department of Physics, University of Ioannina, 45110 Ioannina, Greece.
  • Sainis I; Cancer Biobank Center, University of Ioannina, 45110 Ioannina, Greece.
  • Zoumpoulakis P; Laboratory of Chemistry, Analysis and Design of Food Processes, Department of Food Science and Technology, University of West Attica, 12243 Attica, Greece.
  • Mavromoustakos T; Organic Chemistry Laboratory, Department of Chemistry, University of Athens Greece, 15571 Athens, Greece.
  • Hadjikakou SK; Section of Inorganic and Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Molecules ; 26(16)2021 Aug 19.
Article em En | MEDLINE | ID: mdl-34443612
Eucalyptus leaves (ELE) and willow bark (WBE) extracts were utilized towards the formation of silver nanoparticles (AgNPs(ELE), AgNPs(WBE)). AgNPs(ELE) and AgNPs(WBE) were dispersed in polymer hydrogels to create pHEMA@AgNPs(ELE)_2 and pHEMA@AgNPs(WBE)_2 using hydroxyethyl-methacrylate (HEMA). The materials were characterized in a solid state by X-ray fluorescence (XRF) spectroscopy, X-ray powder diffraction analysis (XRPD), thermogravimetric differential thermal analysis (TG-DTA), differential scanning calorimetry (DTG/DSC) and attenuated total reflection spectroscopy (ATR-FTIR) and ultraviolet visible (UV-vis) spectroscopy in solution. The antimicrobial potential of the materials was investigated against the Gram-negative bacterial strain Pseudomonas aeruginosa (P. aeruginosa) and the Gram-positive bacterial strain of the genus Staphylococcus epidermidis (S. epidermidis) and Staphylococcus aureus (S. aureus), which are involved in microbial keratitis. The percentage of bacterial viability of P. aeruginosa and S. epidermidis upon their incubation over the pHEMA@AgNPs(ELE)_2 discs is interestingly low (28.3 and 6.8% respectively), while the inhibition zones (IZ) formed are 12.3 ± 1.7 and 13.2 ± 1.2 mm, respectively. No in vitro toxicity of this material towards human corneal epithelial cells (HCEC) was detected. Despite its low performance against S. aureus, pHEMA@AgNPs(ELE)_2 could be an efficient candidate towards the development of contact lenses that reduces microbial infection risk.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prata / Extratos Vegetais / Lentes de Contato / Hidrogéis / Salix / Eucalyptus Tipo de estudo: Etiology_studies / Risk_factors_studies Idioma: En Revista: Molecules Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Grécia

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prata / Extratos Vegetais / Lentes de Contato / Hidrogéis / Salix / Eucalyptus Tipo de estudo: Etiology_studies / Risk_factors_studies Idioma: En Revista: Molecules Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Grécia