Terpenoid treatment in osteoporosis: this is where we have come in research.
Trends Endocrinol Metab
; 32(11): 846-861, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-34481733
ABSTRACT
Lower bone resistance to load is due to the imbalance of bone homeostasis, where excessive bone resorption, compared with bone formation, determines a progressive osteopenia, leading to a high risk of fractures and consequent pain and functional limitations. Terpenoids, with their activities against bone resorption, have recently received increased attention from researchers. They are potentially more suitable for long-term use compared with traditional therapeutics. In this review of the literature of the past 5 years, we provide comprehensive information on terpenoids, with their anti-osteoporotic effects, highlighting molecular mechanisms that are often in epigenetic key and a possible pharmacological use in osteoporosis prevention and treatment.
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Texto completo:
1
Base de dados:
MEDLINE
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
/
Aromoterapia
Assunto principal:
Osteoporose
/
Reabsorção Óssea
/
Fraturas Ósseas
Idioma:
En
Revista:
Trends Endocrinol Metab
Ano de publicação:
2021
Tipo de documento:
Article