The Lipid-Modulating Effect of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression through Regulation of LXR&#945; Activation in Hepatic Cells.

Chen, Pei-Yi; Chao, Tzu-Ya; Hsu, Hao-Jen; Wang, Chih-Yang; Lin, Ching-Yen; Gao, Wan-Yun; Wu, Ming-Jiuan; Yen, Jui-Hung

The Lipid-Modulating Effect of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression through Regulation of LXRα Activation in Hepatic Cells.

Chen, Pei-Yi; Chao, Tzu-Ya; Hsu, Hao-Jen; Wang, Chih-Yang; Lin, Ching-Yen; Gao, Wan-Yun; Wu, Ming-Jiuan; Yen, Jui-Hung.

Afiliação

Chen PY; Center of Medical Genetics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 97004, Taiwan.
Chao TY; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 97004, Taiwan.
Hsu HJ; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 97004, Taiwan.
Wang CY; Department of Life Science, Tzu Chi University, Hualien 97004, Taiwan.
Lin CY; Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University, Taipei 11031, Taiwan.
Gao WY; Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei 11031, Taiwan.
Wu MJ; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 97004, Taiwan.
Yen JH; Institute of Medical Sciences, Tzu Chi University, Hualien 970, Taiwan.

Int J Mol Sci ; 22(18)2021 Sep 12.

Article em En | MEDLINE | ID: mdl-34576019

Assuntos

Proteínas Semelhantes a Angiopoietina/antagonistas & inibidores; Flavonas/farmacologia; Metabolismo dos Lipídeos/efeitos dos fármacos; Receptores X do Fígado/metabolismo; Proteína 3 Semelhante a Angiopoietina; Proteínas Semelhantes a Angiopoietina/metabolismo; Avaliação Pré-Clínica de Medicamentos; Dislipidemias/tratamento farmacológico; Flavonas/uso terapêutico; Células Hep G2; Humanos; Lipase/metabolismo

Palavras-chave

ANGPTL3; LXRα; TG-rich lipoproteins; lipoprotein lipase; tangeretin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flavonas / Metabolismo dos Lipídeos / Receptores X do Fígado / Proteínas Semelhantes a Angiopoietina Tipo de estudo: Prognostic_studies Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Taiwan

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