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Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes.
Lu, Yingjuan J; Wheeler, Leroy W; Chu, Haiyan; Kleindl, Paul J; Pugh, Michael; You, Fei; Rao, Satish; Garcia, Gabriela; Wu, Henry Y; da Cunha, Andre P; Johnson, Richard; Westrick, Elaine; Cross, Vicky; Lloyd, Alex; Dircksen, Christina; Klein, Patrick J; Vlahov, Iontcho R; Low, Philip S; Leamon, Christopher P.
Afiliação
  • Lu YJ; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Wheeler LW; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Chu H; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Kleindl PJ; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Pugh M; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • You F; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Rao S; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Garcia G; Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA.
  • Wu HY; Department of Ophthalmology, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • da Cunha AP; Department of Ophthalmology, Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Johnson R; Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA.
  • Westrick E; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Cross V; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Lloyd A; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Dircksen C; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Klein PJ; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Vlahov IR; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
  • Low PS; Department of Chemistry, Purdue Institute for Drug Discovery, and Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
  • Leamon CP; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.
Cell Rep Med ; 2(10): 100422, 2021 10 19.
Article em En | MEDLINE | ID: mdl-34755134
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 2 de Folato / Ácido Fólico / Antagonistas do Ácido Fólico / Síndrome da Liberação de Citocina / Aminopterina / Macrófagos Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: Cell Rep Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 2 de Folato / Ácido Fólico / Antagonistas do Ácido Fólico / Síndrome da Liberação de Citocina / Aminopterina / Macrófagos Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: Cell Rep Med Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos