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Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes.
Dall, Morten; Hassing, Anna S; Niu, Lili; Nielsen, Thomas S; Ingerslev, Lars R; Sulek, Karolina; Trammell, Samuel A J; Gillum, Matthew P; Barrès, Romain; Larsen, Steen; Poulsen, Steen S; Mann, Matthias; Ørskov, Cathrine; Treebak, Jonas T.
Afiliação
  • Dall M; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Hassing AS; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Niu L; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
  • Nielsen TS; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Ingerslev LR; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Sulek K; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
  • Trammell SAJ; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Gillum MP; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Barrès R; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
  • Larsen S; Department of Biomedical Sciences, Xlab, Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark; Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland.
  • Poulsen SS; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Mann M; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
  • Ørskov C; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Treebak JT; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark. Electronic address: jttreebak@sund.ku.dk.
J Biol Chem ; 297(6): 101388, 2021 12.
Article em En | MEDLINE | ID: mdl-34762911
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / Hepatócitos / Hepatopatia Gordurosa não Alcoólica / NAD Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / Hepatócitos / Hepatopatia Gordurosa não Alcoólica / NAD Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca