A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis.

Luo, Shiwei; Ma, Di; Wei, Ruili; Yao, Wang; Pang, Xinrui; Wang, Ye; Xu, Xiangdong; Wei, Xinhua; Guo, Yuan; Jiang, Xinqing; Yuan, Youyong; Yang, Ruimeng

Luo, Shiwei; Ma, Di; Wei, Ruili; Yao, Wang; Pang, Xinrui; Wang, Ye; Xu, Xiangdong; Wei, Xinhua; Guo, Yuan; Jiang, Xinqing; Yuan, Youyong; Yang, Ruimeng.

Afiliação

Luo S; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Ma D; School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, PR China.
Wei R; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Yao W; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Pang X; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Wang Y; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Xu X; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Wei X; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Guo Y; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China.
Jiang X; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China. Electronic address: eyjiangxq@scut.edu.cn.
Yuan Y; School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou 511442, PR China. Electronic address: yuanyy@scut.edu.cn.
Yang R; Department of Radiology, the Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, PR China. Electronic address: eyruimengyang@scut.edu.cn.

Acta Biomater ; 138: 518-527, 2022 01 15.

Article em En | MEDLINE | ID: mdl-34775124

Assuntos

Ferroptose; Neoplasias; Linhagem Celular Tumoral; Humanos; Peróxido de Hidrogênio; Imageamento por Ressonância Magnética; Estresse Oxidativo; Microambiente Tumoral

Palavras-chave

Chelation; Fenton reaction; Ferroptosis; T(1)-weighted magnetic resonance imaging

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ferroptose / Neoplasias Idioma: En Revista: Acta Biomater Ano de publicação: 2022 Tipo de documento: Article