Vindoline Attenuates Osteoarthritis Progression Through Suppressing the NF-&#954;B and ERK Pathways in Both Chondrocytes and Subchondral Osteoclasts.

Zhu, Meisong; Xu, Qiang; Yang, Xinmin; Zhan, Haibo; Zhang, Bin; Liu, Xuqiang; Dai, Min

Vindoline Attenuates Osteoarthritis Progression Through Suppressing the NF-κB and ERK Pathways in Both Chondrocytes and Subchondral Osteoclasts.

Zhu, Meisong; Xu, Qiang; Yang, Xinmin; Zhan, Haibo; Zhang, Bin; Liu, Xuqiang; Dai, Min.

Afiliação

Zhu M; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.
Xu Q; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.
Yang X; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.
Zhan H; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.
Zhang B; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.
Liu X; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.
Dai M; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, China.

Front Pharmacol ; 12: 764598, 2021.

Article em En | MEDLINE | ID: mdl-35095488

Palavras-chave

ERK pathway; NF-κB pathway; extracellular matrix; osteoarthritis; osteoclastogenesis; vindoline

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China