Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations.

Zhang, Hongyuan; Puviindran, Vijitha; Nadesan, Puviindran; Ding, Xiruo; Shen, Leyao; Tang, Yuning J; Tsushima, Hidetoshi; Yahara, Yasuhito; Ban, Ga I; Zhang, Guo-Fang; Karner, Courtney M; Alman, Benjamin A

Zhang, Hongyuan; Puviindran, Vijitha; Nadesan, Puviindran; Ding, Xiruo; Shen, Leyao; Tang, Yuning J; Tsushima, Hidetoshi; Yahara, Yasuhito; Ban, Ga I; Zhang, Guo-Fang; Karner, Courtney M; Alman, Benjamin A.

Afiliação

Zhang H; Department of Cell Biology, Duke University, Durham, NC, USA.
Puviindran V; Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Nadesan P; Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Ding X; Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Shen L; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA.
Tang YJ; Department of Cell Biology, Duke University, Durham, NC, USA.
Tsushima H; Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Yahara Y; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ban GI; Department of Genetics, Stanford University, Stanford, CA, USA.
Zhang GF; Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan.
Karner CM; Department of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Japan.
Alman BA; Department of Orthopaedic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan.

J Bone Miner Res ; 37(5): 983-996, 2022 05.

Article em En | MEDLINE | ID: mdl-35220602

Assuntos

Neoplasias Ósseas; Condroma; Condrossarcoma; Glutamina; Isocitrato Desidrogenase; Mutação; Animais; Neoplasias Ósseas/genética; Neoplasias Ósseas/metabolismo; Neoplasias Ósseas/patologia; Cartilagem/metabolismo; Condroma/genética; Condroma/metabolismo; Condroma/patologia; Condrossarcoma/genética; Condrossarcoma/metabolismo; Condrossarcoma/patologia; Glutaminase/genética; Glutaminase/metabolismo; Glutamina/genética; Glutamina/metabolismo; Humanos; Isocitrato Desidrogenase/genética; Isocitrato Desidrogenase/metabolismo; Ácidos Cetoglutáricos; Camundongos

Palavras-chave

CARTILAGE TUMORS; CHONDROCYTE DIFFERENTIATION; GLUTAMINE METABOLISM; GROWTH PLATE; ISOCITRATE DEHYDROGENASE

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Condroma / Condrossarcoma / Glutamina / Isocitrato Desidrogenase / Mutação Idioma: En Revista: J Bone Miner Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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