Retinoic acid restores the levels of cellular cholesterol in Leishmania donovani infected macrophages by increasing npc1 and npc2 expressions.

Prakash, Satya; Saini, Sheetal; Kumari, Smita; Singh, Bharat; Kureel, Amit Kumar; Rai, Ambak Kumar

Prakash, Satya; Saini, Sheetal; Kumari, Smita; Singh, Bharat; Kureel, Amit Kumar; Rai, Ambak Kumar.

Afiliação

Prakash S; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, 211004, UP, India.
Saini S; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, 211004, UP, India.
Kumari S; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, 211004, UP, India.
Singh B; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, 211004, UP, India.
Kureel AK; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, 211004, UP, India.
Rai AK; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, 211004, UP, India. Electronic address: ambakrai@mnnit.ac.in.

Biochimie ; 198: 23-32, 2022 Jul.

Article em En | MEDLINE | ID: mdl-35272007

Assuntos

Leishmania donovani; Leishmaniose Visceral; Colesterol/metabolismo; Humanos; Macrófagos/metabolismo; Proteína C1 de Niemann-Pick; Tretinoína/metabolismo; Tretinoína/farmacologia; Proteínas de Transporte Vesicular/genética; Proteínas de Transporte Vesicular/metabolismo

Palavras-chave

Cholesterol; NPCs and RA; Visceral leishmaniasis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leishmania donovani / Leishmaniose Visceral Idioma: En Revista: Biochimie Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

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