Mechanisms and Safety of Antidepressant-Like Effect of Nutmeg in Mice.

Iwata, Naohiro; Kobayashi, Daisuke; Kawashiri, Takehiro; Kubota, Toshio; Kawano, Kotomi; Yamamuro, Yuki; Miyagi, Anna; Deguchi, Yuya; Chijimatsu, Takeshi; Shimazoe, Takao

Iwata, Naohiro; Kobayashi, Daisuke; Kawashiri, Takehiro; Kubota, Toshio; Kawano, Kotomi; Yamamuro, Yuki; Miyagi, Anna; Deguchi, Yuya; Chijimatsu, Takeshi; Shimazoe, Takao.

Afiliação

Iwata N; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.
Kobayashi D; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.
Kawashiri T; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.
Kubota T; Center of Pharmaceutical Care for Community Health, Daiichi University of Pharmacy.
Kawano K; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.
Yamamuro Y; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.
Miyagi A; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.
Deguchi Y; Faculty of Pharmaceutical Sciences, Nagasaki International University.
Chijimatsu T; Sasaki Food Co., Ltd.
Shimazoe T; Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University.

Biol Pharm Bull ; 45(6): 738-742, 2022 Jun 01.

Article em En | MEDLINE | ID: mdl-35314522

Assuntos

Myristica; Animais; Antidepressivos/farmacologia; Antidepressivos/uso terapêutico; Depressão/tratamento farmacológico; Elevação dos Membros Posteriores/métodos; Camundongos; Myristica/metabolismo; Serotonina/metabolismo; Antagonistas da Serotonina/farmacologia; Natação

Palavras-chave

Ames test; acute toxicity test; antidepressant; central nervous system; nutmeg n-hexane extract; tail suspension test

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Myristica Idioma: En Revista: Biol Pharm Bull Ano de publicação: 2022 Tipo de documento: Article