Two new triterpenoid saponins from <i>Bupleurum marginatum</i> Wall. ex DC.

Luo, Ke; Dai, Rong-Ji; Wang, Zhi; Zeng, Yan-Bo; Deng, Yu-Lin; Lv, Fang

Two new triterpenoid saponins from Bupleurum marginatum Wall. ex DC.

Luo, Ke; Dai, Rong-Ji; Wang, Zhi; Zeng, Yan-Bo; Deng, Yu-Lin; Lv, Fang.

Afiliação

Luo K; Beijing Key Labrotary for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing, China.
Dai RJ; Beijing Key Labrotary for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing, China.
Wang Z; Beijing Key Labrotary for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing, China.
Zeng YB; Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.
Deng YL; Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.
Lv F; Beijing Key Labrotary for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing, China.

Nat Prod Res ; 37(20): 3380-3387, 2023.

Article em En | MEDLINE | ID: mdl-35574628

ABSTRACT

ABSTRACT

Two new triterpenoid saponins (1 and 2), together with two known saponins (3 and 4) were isolated from Bupleurum marginatum Wall. ex DC. Their structures were elucidated by the comprehensive spectroscopic analysis. Compounds 1 and 2 represented the rare example of an oleanane-type triterpenoid with two sugar moieties at C-3 and C-28. The cytotoxic activity of four compounds was evaluated against normal heptocell BRL-3A in vitro.

Palavras-chave

Bupleurum marginatum Wall. ex DC.; cytotoxicity; medicinal plant; triterpenoid saponins

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Nat Prod Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China