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A single-molecular ruthenium(II) complex-based NIR-II fluorophore for enhanced chemo-photothermal therapy.
Li, Qianqian; Liu, Yishen; Zhao, Bingshan; Lei, Jiapeng; Lu, Siyu; Gong, Wanxia; Liang, Ke; Wu, Junzhu; Hong, Xuechuan; Xiao, Yuling.
Afiliação
  • Li Q; Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. xiaoyl@whu.edu.cn.
  • Liu Y; Hubei Key Laboratory for Processing and Application of Catalytic Materials, Huanggang Normal University, Huanggang, 438000, China.
  • Zhao B; Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. xiaoyl@whu.edu.cn.
  • Lei J; Hubei Key Laboratory for Processing and Application of Catalytic Materials, Huanggang Normal University, Huanggang, 438000, China.
  • Lu S; School of Basic Medical Sciences, Nanchang University, Nanchang, 330031, P. R. China.
  • Gong W; Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. xiaoyl@whu.edu.cn.
  • Liang K; Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. xiaoyl@whu.edu.cn.
  • Wu J; Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. xiaoyl@whu.edu.cn.
  • Hong X; State Key Laboratory of Virology, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE), Hubei Provincial Key Laboratory of Developmentally Originated Disease, Center for Experimental Basic Medical Education, Wuhan 430071, China.
  • Xiao Y; Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China. xiaoyl@whu.edu.cn.
Chem Commun (Camb) ; 58(45): 6546-6549, 2022 Jun 01.
Article em En | MEDLINE | ID: mdl-35579558
Novel NIR-II Ru(II) polypyridyl fluorophore Ru-1 dots for synergistic chemo-photothermal therapy against 4T1 tumors were designed and synthesized. Guided by in vivo NIR-II fluorescence imaging, the synergistic therapeutic efficacy, intracellular delivery, and biodistribution of the Ru-1 dots were precisely tracked in real-time.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rutênio / Nanopartículas Idioma: En Revista: Chem Commun (Camb) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rutênio / Nanopartículas Idioma: En Revista: Chem Commun (Camb) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China