Ziziphus mauritiana Lam attenuates inflammation via downregulating NF&#954;B pathway in LPS-stimulated RAW 264.7 macrophages & OVA-induced airway inflammation in mice models.

Ramar, Mohan Kumar; Henry, Linda Jeeva Kumari; Ramachandran, Shiyamsundar; Chidambaram, Kumarappan; Kandasamy, Ruckmani

Ziziphus mauritiana Lam attenuates inflammation via downregulating NFκB pathway in LPS-stimulated RAW 264.7 macrophages & OVA-induced airway inflammation in mice models.

Ramar, Mohan Kumar; Henry, Linda Jeeva Kumari; Ramachandran, Shiyamsundar; Chidambaram, Kumarappan; Kandasamy, Ruckmani.

Afiliação

Ramar MK; Laboratory of Pulmonary Research, National Facility for Drug Development (NFDD), Department of Pharmaceutical Technology, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India.
Henry LJK; Laboratory of Pulmonary Research, National Facility for Drug Development (NFDD), Department of Pharmaceutical Technology, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India.
Ramachandran S; Department of Biotechnology, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India.
Chidambaram K; Department of Pharmacology & Toxicology, School of Pharmacy, King Khalid University, Abha, 68589, Saudi Arabia.
Kandasamy R; Laboratory of Pulmonary Research, National Facility for Drug Development (NFDD), Department of Pharmaceutical Technology, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli, 620024, Tamil Nadu, India. Electronic address: hodpharma@gmail.com.

J Ethnopharmacol ; 295: 115445, 2022 Sep 15.

Article em En | MEDLINE | ID: mdl-35690340

Assuntos

Asma; Ziziphus; Animais; Asma/induzido quimicamente; Asma/tratamento farmacológico; Asma/metabolismo; Citocinas/metabolismo; Inflamação/induzido quimicamente; Inflamação/tratamento farmacológico; Inflamação/prevenção & controle; Lipopolissacarídeos/toxicidade; Macrófagos/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; NF-kappa B/metabolismo; Ovalbumina; Espécies Reativas de Oxigênio; Terpenos/farmacologia; Terpenos/uso terapêutico

Palavras-chave

Asthma; Eosinophils; Macrophages; Terpenoids; Ziziphus mauritiana Lam

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Ziziphus Tipo de estudo: Prognostic_studies Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

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