Acupuncture and osteopathic medicine for atopic dermatitis: a three-armed, randomized controlled explorative clinical trial.
Clin Exp Dermatol
; 47(12): 2166-2175, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35875898
ABSTRACT
BACKGROUND:
Patients with atopic dermatitis (AD) frequently use acupuncture (ACU) and osteopathic medicine (OM), although their therapeutic benefits are unclear.AIM:
To investigate the effectiveness of ACU and OM in patients with AD.METHODS:
In a three-armed, single-centre, randomized controlled open explorative clinical trial, adult patients with AD received ACU, OM or no study intervention (control group; CG) plus routine care. Outcomes included disease severity (SCORing Atopic Dermatitis; SCORAD), itching intensity (visual analogue scale; VAS), frequency of topical corticosteroid (TCS) use over 7 days and cost-effectiveness. Endpoints were analysed by analysis of covariance adjusted for the respective baseline value and TCS use.RESULTS:
Overall, 121 patients (92 women, 29 men) with a mean ± SD age of 31.4 ± 10.5 years were randomized. After 12 weeks, the adjusted means (95% CI) for ACU, OM and control were, respectively, 22.3 (18.3-26.3), 26.4 (22.6-30.2) and 23.7 (19.9-27.5) for SCORAD (P = 0.32); 27.9 (19.5-36.4), 35.0 (26.9-43.0) and 42.3 (34.7-50.0) for VAS itching (P < 0.05); and 2.3 (0.8-3.9), 1.9 (0.4-3.5) and 4.3 (2.6-6.0), for TCS use (P = 0.10). ACU and OM were not cost-effective compared with the CG.CONCLUSION:
Although no differences in disease severity were found, our findings indicate that ACU might reduce itching in patients with AD. Furthermore, ACU and OM showed a trend towards reducing TCS use.
Texto completo:
1
Base de dados:
MEDLINE
Medicinas Tradicionais:
Medicinas_tradicionales_de_asia
/
Medicina_china
Medicinas Complementares:
Medicina_osteopatica
Métodos Terapêuticos e Terapias MTCI:
Terapias_manuales
Assunto principal:
Medicina Osteopática
/
Terapia por Acupuntura
/
Dermatite Atópica
/
Fármacos Dermatológicos
Tipo de estudo:
Clinical_trials
Idioma:
En
Revista:
Clin Exp Dermatol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Alemanha