Your browser doesn't support javascript.
loading
A review of the anti-diabetic potential of saffron.
Sani, Anis; Tajik, Ali; Seiiedi, Seiied Sina; Khadem, Razieh; Tootooni, Haniye; Taherynejad, Mohammadhossein; Sabet Eqlidi, Nasim; Alavi Dana, Seyyed Mohammad Matin; Deravi, Niloofar.
Afiliação
  • Sani A; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Tajik A; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Seiiedi SS; Student Research Committee, Department of Medicine, Ardabil branch, Islamic Azad University, Ardabil, Iran.
  • Khadem R; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Tootooni H; Student Research Committee, Varastegan Institute for Medical Sciences, Mashhad, Iran.
  • Taherynejad M; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Sabet Eqlidi N; Student Research Committee, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
  • Alavi Dana SMM; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Deravi N; Student Research committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nutr Metab Insights ; 15: 11786388221095223, 2022.
Article em En | MEDLINE | ID: mdl-35911474
ABSTRACT
Diabetes mellitus is one of the most prevalent metabolic disorders that affect people of all genders, ages, and races. Medicinal herbs have gained attention from researchers and have been widely investigated for their antidiabetic potential. Saffron (Crocus sativus L.) and its main constituents, that is, crocin and crocetin, are natural carotenoid compounds, widely known to possess a wide spectrum of properties and induce pleiotropic anti-inflammatory, anti-oxidative, and neuro-protective effects. An increasing number of experimental, animal and human studies have investigated the effects and mechanism of action of these compounds and their potential therapeutic use in the treatment of diabetes. This narrative review presents the key findings of published clinical studies that examined the effects of saffron and/or its constituents in the context of diabetes mellitus. Moreover, an overview of the proposed underlying mechanisms mediating these effects, the medicinal applications of saffron, and the new findings regarding its effect on diabetes and various cellular and molecular mechanisms of action will be debated.
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Nutr Metab Insights Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Nutr Metab Insights Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irã