Circadian rhythm in prostate cancer: time to take notice of the clock.
Asian J Androl
; 25(2): 184-191, 2023.
Article
em En
| MEDLINE
| ID: mdl-36073562
ABSTRACT
The circadian clock is an evolutionary molecular product that is associated with better adaptation to changes in the external environment. Disruption of the circadian rhythm plays a critical role in tumorigenesis of many kinds of cancers, including prostate cancer (PCa). Integrating circadian rhythm into PCa research not only brings a closer understanding of the mechanisms of PCa but also provides new and effective options for the precise treatment of patients with PCa. This review begins with patterns of the circadian clock, highlights the role of the disruption of circadian rhythms in PCa at the epidemiological and molecular levels, and discusses possible new approaches to PCa therapy that target the circadian clock.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Ritmo Circadiano
/
Relógios Circadianos
Idioma:
En
Revista:
Asian J Androl
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China