Cryptotanshinone inhibits ovarian tumor growth and metastasis by degrading c-Myc and attenuating the FAK signaling pathway.

Guo, Huijun; Zhang, Wenjing; Wang, Jiaxing; Zhao, Guannan; Wang, Yaohong; Zhu, Bing-Mei; Dong, Peixin; Watari, Hidemichi; Wang, Baojin; Li, Wei; Tigyi, Gabor; Yue, Junming

Guo, Huijun; Zhang, Wenjing; Wang, Jiaxing; Zhao, Guannan; Wang, Yaohong; Zhu, Bing-Mei; Dong, Peixin; Watari, Hidemichi; Wang, Baojin; Li, Wei; Tigyi, Gabor; Yue, Junming.

Afiliação

Guo H; Department of Pathogen Biology and Immunology, College of Life Science, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Zhang W; Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Wang J; Department of Genetics, Genomics and Informatics, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Zhao G; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, United States.
Wang Y; Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.
Zhu BM; Department of Pathology, Immunology and Microbiology, Vanderbilt University, Nashville, TN, United States.
Dong P; Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
Watari H; Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Wang B; Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Li W; Department of Gynecology and Obstetrics, Third Affiliated Hospital, Zhengzhou University, Zhengzhou, China.
Tigyi G; Department of Pharmaceutical Sciences, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN, United States.
Yue J; Department of Physiology, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, United States.

Front Cell Dev Biol ; 10: 959518, 2022.

Article em En | MEDLINE | ID: mdl-36247016

Palavras-chave

FAK; c-Myc; cryptotanshinone; metastasis; ovarian cancer; ubiquitination

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Idioma: En Revista: Front Cell Dev Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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