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Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing.
Fossa, Paola; Uggeri, Matteo; Orro, Alessandro; Urbinati, Chiara; Rondina, Alessandro; Milanesi, Maria; Pedemonte, Nicoletta; Pesce, Emanuela; Padoan, Rita; Ford, Robert C; Meng, Xin; Rusnati, Marco; D'Ursi, Pasqualina.
Afiliação
  • Fossa P; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, 16132 Genoa, Italy.
  • Uggeri M; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, 16132 Genoa, Italy.
  • Orro A; Institute for Biomedical Technologies, National Research Council (ITB-CNR), 20054 Segrate, Italy.
  • Urbinati C; Institute for Biomedical Technologies, National Research Council (ITB-CNR), 20054 Segrate, Italy.
  • Rondina A; Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Milanesi M; Institute for Biomedical Technologies, National Research Council (ITB-CNR), 20054 Segrate, Italy.
  • Pedemonte N; Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
  • Pesce E; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Padoan R; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Ford RC; Department of Pediatrics, Regional Support Centre for Cystic Fibrosis, Children's Hospital-ASST Spedali Civili, University of Brescia, 25123 Brescia, Italy.
  • Meng X; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
  • Rusnati M; Cellular Degradation Systems Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • D'Ursi P; Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Int J Mol Sci ; 23(20)2022 Oct 14.
Article em En | MEDLINE | ID: mdl-36293130
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulador de Condutância Transmembrana em Fibrose Cística / Fibrose Cística Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulador de Condutância Transmembrana em Fibrose Cística / Fibrose Cística Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália