Wuzi-Yanzong-Wan prevents oligoasthenospermia due to TAp73 suppression by affecting cellular junction remodeling in testicular tissue in mice.

Wu, Deling; Wang, Tongsheng; Liu, Hongjuan; Xu, Fengqing; Xie, Songzi; Tong, Xiaohui; Li, Li; Peng, Daiyin; Kong, Lingyi

Wu, Deling; Wang, Tongsheng; Liu, Hongjuan; Xu, Fengqing; Xie, Songzi; Tong, Xiaohui; Li, Li; Peng, Daiyin; Kong, Lingyi.

Afiliação

Wu D; School of Pharmacy, Anhui University of Chinese Medicine, Anhui Province Key Laboratory of Chinese Medical Formula, Hefei, China; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical U
Wang T; School of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China.
Liu H; School of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China.
Xu F; School of Pharmacy, Anhui University of Chinese Medicine, Anhui Province Key Laboratory of Chinese Medical Formula, Hefei, China.
Xie S; School of Pharmacy, Anhui University of Chinese Medicine, Anhui Province Key Laboratory of Chinese Medical Formula, Hefei, China.
Tong X; School of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China.
Li L; School of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China.
Peng D; School of Pharmacy, Anhui University of Chinese Medicine, Anhui Province Key Laboratory of Chinese Medical Formula, Hefei, China. Electronic address: pengdy@ahtcm.edu.cn.
Kong L; Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China. Electronic address: cpu_lykong@126.com.

J Ethnopharmacol ; 302(Pt A): 115867, 2023 Feb 10.

Article em En | MEDLINE | ID: mdl-36341818

Assuntos

Sêmen; Testículo; Masculino; Camundongos; Animais; Nectinas/metabolismo; Ocludina/metabolismo; Camundongos Endogâmicos C57BL; Testículo/metabolismo; Espermatogênese; Junções Intercelulares; Caderinas/genética; Caderinas/metabolismo; Integrinas/metabolismo

Palavras-chave

Cellular junctions; Ectoplasmic specialization; Oligoasthenospermia; TAp73; Tight junction; Wuzi-Yanzong-Wan

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sêmen / Testículo Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2023 Tipo de documento: Article