Large-scale computational screening of Indian medicinal plants reveals Cassia angustifolia to be a potentially anti-diabetic.

In-house database phytochemicals preparation using Indian medicinal plants for repurposing plant therapeutics screening.Virtual screening of in-house database against alpha amylase for anti-diabetic therapeutics.The highest affinity plants Cassia angustifolia were identified, collected, processed four solvent extracts, along with qualitative and quantitative estimations.All plant extracts are subjected to botanical and biological experimental perspective.Advanced molecular dynamics simulations are used to understand the non-bonding interactions of phytochemicals with alpha amylase.