Validation of baicalein and oridonin as nonspecific SARS-CoV-2 main protease inhibitors.

Yan, Haohao; Zhang, Rui; Yan, Gangan; Liu, Xiaoping; Li, Ni; Chen, Yunyu

Yan, Haohao; Zhang, Rui; Yan, Gangan; Liu, Xiaoping; Li, Ni; Chen, Yunyu.

Afiliação

Yan H; Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.
Zhang R; Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.
Yan G; Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.
Liu X; Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.
Li N; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Chen Y; Institute for Drug Screening and Evaluation, Wannan Medical College, Wuhu, 241002, China.

Phytother Res ; 38(3): 1161-1164, 2024 Mar.

Article em En | MEDLINE | ID: mdl-37042347

Assuntos

COVID-19; Proteases 3C de Coronavírus; Diterpenos do Tipo Caurano; Flavanonas; Humanos; SARS-CoV-2; Inibidores de Proteases; Simulação de Acoplamento Molecular; Antivirais

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diterpenos do Tipo Caurano / Flavanonas / Proteases 3C de Coronavírus / COVID-19 Idioma: En Revista: Phytother Res Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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