Withania somnifera seed oil exhibits antibiofilm properties against drug-resistant Candida auris clinical isolate through modulation in cell permeability.

Balkrishna, Acharya; Kharayat, Bhawana; Rastogi, Shubhangi; Kabdwal, Manisha; Haldar, Swati; Varshney, Anurag

Balkrishna, Acharya; Kharayat, Bhawana; Rastogi, Shubhangi; Kabdwal, Manisha; Haldar, Swati; Varshney, Anurag.

Afiliação

Balkrishna A; Drug Discovery and Development Division, Patanjali Research Institute, Roorkee-Haridwar Road, Haridwar 249405, India.
Kharayat B; Department of Allied and Applied Sciences, University of Patanjali, NH-58, Haridwar 249405, India.
Rastogi S; Patanjali Yog Peeth (UK) Trust, 40 Lambhill Street, Kinning Park, Glasgow, G41 1AU, United Kingdom.
Kabdwal M; Drug Discovery and Development Division, Patanjali Research Institute, Roorkee-Haridwar Road, Haridwar 249405, India.
Haldar S; Drug Discovery and Development Division, Patanjali Research Institute, Roorkee-Haridwar Road, Haridwar 249405, India.
Varshney A; Drug Discovery and Development Division, Patanjali Research Institute, Roorkee-Haridwar Road, Haridwar 249405, India.

J Appl Microbiol ; 134(6)2023 Jun 01.

Article em En | MEDLINE | ID: mdl-37096387

Assuntos

Candida; Withania; Candida auris; Antifúngicos/farmacologia; Biofilmes; Óleos de Plantas/farmacologia; Testes de Sensibilidade Microbiana

Palavras-chave

Withania somnifera seed oil; WSSO; antibiofilm activity; antifungalfungistatic activity; ergosterol binding; fluconazole-resistant Candida auris; scanning electron microscopy; sorbitol protection; time-kill

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Candida / Withania Idioma: En Revista: J Appl Microbiol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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