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Folate-mediated magnetic and pH/GSH dual-responsive metal-polymer-coordinated nanocomplexes for joint chemo/chemodynamic anti-breast cancer therapy.
Lan, Zhuo; Tan, Xiaopei; Chen, Cheng; Cao, Yu; Wan, Yu; Feng, Shun.
Afiliação
  • Lan Z; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
  • Tan X; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
  • Chen C; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
  • Cao Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
  • Wan Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
  • Feng S; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China.
J Biomater Sci Polym Ed ; 34(15): 2041-2059, 2023 10.
Article em En | MEDLINE | ID: mdl-37104876
An intelligent drug carrier system FA-ß-CD/DOX@Cu2+@GA@Fe3O4 was synthesized by skillfully introducing metal ions as bridge base.Magnetic and receptor-targeting delivery of doxorubicin.It can induce the specific release of therapeutic agents through pH/GSH stimulation.Achieving an efficient tumor-specific chemotherapy/CDT therapy.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polímeros / Neoplasias da Mama Idioma: En Revista: J Biomater Sci Polym Ed Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polímeros / Neoplasias da Mama Idioma: En Revista: J Biomater Sci Polym Ed Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China