Jiedu Quyu Decoction mitigates monocrotaline-induced right-sided heart failure associated with pulmonary artery hypertension by inhibiting NLRP3 inflammasome in rats.

Ma, Qiuxiao; Wang, Min; Li, Lanfang; Zhang, Xinyu; Cui, Lixin; Mou, Junyu; Sun, Guibo; Zhang, Qiong

Ma, Qiuxiao; Wang, Min; Li, Lanfang; Zhang, Xinyu; Cui, Lixin; Mou, Junyu; Sun, Guibo; Zhang, Qiong.

Afiliação

Ma Q; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. Electronic address: 582856368@qq.com.
Wang M; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. Electronic address: mwang@implad.ac.cn.
Li L; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. Electronic address: 15265918905@163.com.
Zhang X; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: 411235340@qq.com.
Cui L; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: 18811356129@163.com.
Mou J; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. Electronic address: mjy5197664@163.com.
Sun G; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100193, China. Electronic address: sunguibo@126.com.
Zhang Q; Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: zhangq810@263.net.

J Ethnopharmacol ; 313: 116556, 2023 Sep 15.

Article em En | MEDLINE | ID: mdl-37142147

Assuntos

Insuficiência Cardíaca; Hipertensão Pulmonar; Hipertensão Arterial Pulmonar; Ratos; Animais; Inflamassomos/metabolismo; Interleucina-18/análise; Interleucina-18/uso terapêutico; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Monocrotalina/uso terapêutico; Ratos Sprague-Dawley; Hipertensão Pulmonar/induzido quimicamente; Hipertensão Pulmonar/tratamento farmacológico; Hipertensão Pulmonar/metabolismo; Artéria Pulmonar/metabolismo; Insuficiência Cardíaca/tratamento farmacológico; RNA Mensageiro; Biomarcadores; Interleucina-1beta/metabolismo

Palavras-chave

Cardioprotection; Jiedu Quyu Decoction; NLRP3; Pulmonary arterial hypertension; Right-sided heart failure; Traditional Chinese medicine

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Assunto principal: Hipertensão Arterial Pulmonar / Insuficiência Cardíaca / Hipertensão Pulmonar Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2023 Tipo de documento: Article

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