Centella triterpenes cream as a potential drug for the treatment of hypertrophic scar through inhibiting the phosphorylation of STAT3: A network pharmacology analysis and in vitro experiments.

Tan, Ming; Wu, Dan; Zhou, Yanshijing; Duan, Bo

Tan, Ming; Wu, Dan; Zhou, Yanshijing; Duan, Bo.

Afiliação

Tan M; Department of Plastic and Cosmetic Surgery, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wu D; Department of Plastic and Cosmetic Surgery, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhou Y; Department of Plastic and Cosmetic Surgery, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Duan B; Department of Plastic and Cosmetic Surgery, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

J Cosmet Dermatol ; 22(12): 3511-3519, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37563868

Assuntos

Centella; Cicatriz Hipertrófica; Humanos; Cicatriz Hipertrófica/tratamento farmacológico; Fator de Crescimento Transformador beta1/metabolismo; Fosforilação; Farmacologia em Rede; Fibroblastos; Fator de Transcrição STAT3/metabolismo; Fator de Transcrição STAT3/farmacologia

Palavras-chave

STAT3; centella triterpenes cream; hypertrophic scars (HS); network pharmacology

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Texto completo: 1 Base de dados: MEDLINE Métodos Terapêuticos e Terapias MTCI: Plantas_medicinales Assunto principal: Cicatriz Hipertrófica / Centella Idioma: En Revista: J Cosmet Dermatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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