Antidiabetic Effect of Star Anise (Illicium verum) in Streptozotocin-induced Diabetic Rats.
Cardiovasc Hematol Disord Drug Targets
; 23(2): 92-98, 2023.
Article
em En
| MEDLINE
| ID: mdl-37612867
ABSTRACT
AIM:
The current study aimed to evaluate the antidiabetic potential of Illicium verum fruits.BACKGROUND:
Illicium verum fruits are frequently used by the Moroccan population in the treatment of diabetes.METHODS:
The antihyperglycemic effect of the aqueous extract of Illicium verum fruits (AEIVF) in rats was assessed. The effects of AEIVF (20 mg/kg) on glycemia and lipid profile as well as its phytochemical and antioxidant properties were evaluated.RESULTS:
In normal and diabetic rats, AEIVF reduced blood glucose levels 6 hours after administration. Furthermore, after 7 days of treatment, glycemia was lowered in diabetic rats, and this extract exhibited an antioxidant activity.CONCLUSION:
The study shows that Illicium verum possesses a potent antidiabetic activity. In addition, the toxicity of AEIVF was evaluated and the LD50 value was found to be greater than the 2 g/kg dose.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Illicium
/
Diabetes Mellitus Experimental
Idioma:
En
Revista:
Cardiovasc Hematol Disord Drug Targets
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Marrocos