[Mechanism of Qilongtian Capsules in treatment of acute lung injury based on network pharmacology prediction and experimental validation].

Xie, Ying; Su, Xue-Rong; Zhou, Tong; Liang, Yi-Yao; Wu, Yang-Qian; Wan, Yi; Lu, Tu-Lin; Zhao, Xiao-Li; Li, Zheng-Yan

Xie, Ying; Su, Xue-Rong; Zhou, Tong; Liang, Yi-Yao; Wu, Yang-Qian; Wan, Yi; Lu, Tu-Lin; Zhao, Xiao-Li; Li, Zheng-Yan.

Afiliação

Xie Y; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Su XR; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Zhou T; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Liang YY; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Wu YQ; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Wan Y; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Lu TL; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Zhao XL; School of Pharmacy,Nanjing University of Chinese Medicine Nanjing 210046, China.
Li ZY; Kunming Municipal Hospital of Chinese Medicine Kunming 650051,China.

Zhongguo Zhong Yao Za Zhi ; 48(15): 4187-4200, 2023 Aug.

Article em Zh | MEDLINE | ID: mdl-37802787

Assuntos

Lesão Pulmonar Aguda; Medicamentos de Ervas Chinesas; Ginsenosídeos; Humanos; Fator de Necrose Tumoral alfa; Caspase 3; Metaloproteinase 9 da Matriz; Interleucina-6; Simulação de Acoplamento Molecular; Farmacologia em Rede; Espécies Reativas de Oxigênio; Espectrometria de Massas em Tandem; Lesão Pulmonar Aguda/tratamento farmacológico; Lesão Pulmonar Aguda/genética; Cápsulas; RNA Mensageiro; Medicamentos de Ervas Chinesas/farmacologia

Palavras-chave

Qilongtian Capsules; UPLC-Q-TOF-MS/MS; acute lung injury; macrophage RAW264.7; molecular docking; network pharmacology

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Texto completo: 1 Base de dados: MEDLINE Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas Assunto principal: Medicamentos de Ervas Chinesas / Ginsenosídeos / Lesão Pulmonar Aguda Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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