Vitamin intake and periodontal disease: a meta-analysis of observational studies.
BMC Oral Health
; 24(1): 117, 2024 Jan 20.
Article
em En
| MEDLINE
| ID: mdl-38245765
ABSTRACT
OBJECTIVE:
A meta-analysis was performed to assess the epidemiological correlation between dietary intake of various types of vitamin intake and the risk of periodontal disease.METHODS:
A comprehensive computerized search was conducted in eight databases, namely PubMed, Web of Science, Embase, Cochrane Library, China Biology Medicine Disc, CNKI, VIP, and WanFang Database, and a random effect model was applied to combine pooled odds ratio (ORs) with corresponding 95% confidence intervals (CIs) of the included studies, and the sensitivity analysis was performed to explore the impact of a single study on the comprehensive results.RESULTS:
We finally included 45 effect groups from 23 observational studies, with a total number of study participants of 74,488. The results showed that higher levels of vitamin A (OR 0.788, 95% CI 0.640-0.971), vitamin B complex (OR 0.884, 95% CI 0.824-0.948), vitamin C (OR 0.875, 95% CI 0.775-0.988), vitamin D (OR 0.964, 95% CI 0.948-0.981), and vitamin E (OR 0.868, 95% CI 0.776-0.971) intake all were negatively correlated with periodontal disease. After removing each study, leave-one-out sensitivity analysis indicated no significant change in the overall results of any of the five meta-analyses.CONCLUSIONS:
The results from this meta-analysis demonstrated a negative association between high-dose vitamin A, vitamin B complex, vitamin C, vitamin D, and vitamin E consumption and the likelihood of developing periodontal disease, revealing the significant role of vitamins in preventing periodontal disease.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Periodontais
/
Complexo Vitamínico B
Tipo de estudo:
Etiology_studies
/
Observational_studies
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Systematic_reviews
Idioma:
En
Revista:
BMC Oral Health
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China