[Device for measuring paw edema in rats and mice]. / Pribor dlia izmereniia oteka lapy u krys i myshei.

ABSTRACT

An unsophisticated highly precise mercuric electron-mechanic oncometer is proposed. It is intended for measuring paw edema in small laboratory animals during screening of new antiphlogistics. The device consists of two communicating vessels. The change in the mercury level after paw immersion transforms to the electrical signal by the induction technique. The controller of the displacement consists of a float, a ferromagnetic rod and a coil with windings. The movement of the rod changes mutual induction of the windings, amplitude modulation of the carrier frequency of the generator and unbalance of the differential diode bridge. The magnitude of the unbalance is recorded with the aid of appropriate units.