Genotoxic effects of the chlorinated hydroxyfuranones 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and 3,4-dichloro-5-hydroxy-2[5H]-furanone in Tradescantia micronucleus assays.
Mutat Res
; 346(3): 181-6, 1995 Mar.
Article
em En
| MEDLINE
| ID: mdl-7700282
ABSTRACT
This is the first report of clastogenic effects of chlorinated hydroxyfuranones (CHFs) in plants. Two byproducts of water chlorination, 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) and 3,4-dichloro-5-hydroxy-2[5H]-furanone (MA) induced a dose dependent increase of micronuclei (MN) in pollen mother cells of Tradescantia when doses up to 100 micrograms MX and 500 micrograms MA were applied directly to the inflorescences. In contrast, exposure of the stems in aqueous solutions containing up to 1 mg/l MX and 10 mg/l MA did not cause a positive response.
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Base de dados:
MEDLINE
Medicinas Complementares:
Homeopatia
Assunto principal:
Plantas
/
Testes para Micronúcleos
/
Furanos
/
Mutagênicos
Idioma:
En
Revista:
Mutat Res
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Áustria