Identification of basic fibroblast growth factor-like immunoreactivity in panax ginseng extract: investigation of its molecular properties.
Biosci Biotechnol Biochem
; 60(4): 584-8, 1996 Apr.
Article
em En
| MEDLINE
| ID: mdl-8829523
ABSTRACT
Basic fibroblast growth factor (bFGF)-like immunoreactivity was detected in extracts of Panax ginseng root by using a sensitive two-site enzyme immunoassay specific for human bFGF (hbFGF). In an investigation of the molecular properties of this bFGF-like molecule (bFGF-LI), the bFGF-LI and hbFGF were found to be equivalent with respect to antigenicity, molecular weight, isoelectric point, affinity for binding to heparin, and mitogenic activity toward BALB/c3T3 fibroblasts. The identification of this bFGF-LI molecule in Panax ginseng root helps to explain various activities of the traditional Chinese medicine ginseng.
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Base de dados:
MEDLINE
Medicinas Tradicionais:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Plantas Medicinais
/
Extratos Vegetais
/
Fator 2 de Crescimento de Fibroblastos
/
Panax
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Idioma:
En
Revista:
Biosci Biotechnol Biochem
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Japão