Experimental inoculation of foals and pigs with an enterotoxigenic E. coli isolated from a foal.
Vet Microbiol
; 52(3-4): 249-57, 1996 Oct.
Article
em En
| MEDLINE
| ID: mdl-8972050
ABSTRACT
Hemolytic E. coli strain 807-13, O149NMK88(STb+, LT+), was isolated from the feces of a neonatal diarrheic foal. E. coli 807-13 was examined for adhesion to brush border membranes (BBM) from foals, adult horses and pigs, and its pathogenicity was assessed in neonatal foals and pigs. E. coli 807-13 did not adhere to equine BBM but adhered to pig BBM. It did not cause diarrhea nor did it colonize the intestinal epithelium of 3 colostrum-deprived and 3 suckled foals challenged at 24 h of age. Acute ulcerative gastritis and acute suppurative gastritis were observed in 2 colostrum-deprived challenged foals, and acute neutrophilic enteritis was observed in 1 colostrum-deprived and in 1 suckled challenged foal. No similar histopathologic lesions were detected in the control foals. Both gnotobiotic and suckled pigs developed diarrhea after challenge exposure to E. coli 807-13 and the intestinal epithelium of the pigs was colonized. Histopathologic evidence of gastritis and enteritis among the foals indicated some complicity of E. coli 807-13 in foal enteric disease.
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Base de dados:
MEDLINE
Assunto principal:
Doenças dos Suínos
/
Diarreia
/
Escherichia coli
/
Infecções por Escherichia coli
/
Doenças dos Cavalos
Idioma:
En
Revista:
Vet Microbiol
Ano de publicação:
1996
Tipo de documento:
Article
País de afiliação:
Estados Unidos