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[Nucleolar apparatus of neurosecretory cells in the hypothalamus of rats of different age during acute immobilization stress]. / Kharakteristika iadryshkovogo apparata neirosekretornykh kletok gipotalamusa u krys raznogo vosrasta pri ostroi immobilizatsii zhivotnykh.
Bazhanova, E D; Chernigovskaia, E V; Danilova, O A; Bazhanov, I A.
Afiliação
  • Bazhanova ED; Institute of Evolutionary Biochemistry and Physiology, Russian Academy of Sciences, St. Petersburg.
Tsitologiia ; 40(4): 248-55, 1998.
Article em Ru | MEDLINE | ID: mdl-9644759
To determine condition and adaptive capacity of cell nucleoli at ageing, the effect of acute immobilization on the hypothalamic neurosecretory cells was investigated in young and old male Wistar rats. Using immunohistochemical methods and nucleolometry we have shown that: 1) the nuclear volume in all neurosecretory cells is increased; 2) the share of cells, containing nucleoli with marginal position or multiple nucleoli in the nuclei, displays opposite changes in young and in old rats under stress condition. We suppose that adaptive mechanisms are different in young and old animals. Although, both kinds of morphological reorganization result in the increase in functional activity.
Assuntos
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Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Nucléolo Celular / Hipotálamo / Sistemas Neurossecretores Idioma: Ru Revista: Tsitologiia Ano de publicação: 1998 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Nucléolo Celular / Hipotálamo / Sistemas Neurossecretores Idioma: Ru Revista: Tsitologiia Ano de publicação: 1998 Tipo de documento: Article