UPLC/Q-TOF-MS(E) based analysis of chemical composition of banxia xiexin decoction / 药学学报
Acta Pharmaceutica Sinica
; (12): 526-531, 2013.
Article
em Zh
| WPRIM
| ID: wpr-235633
Biblioteca responsável:
WPRO
ABSTRACT
In order to clarify the chemical composition and source of Banxia Xiexin decoction quickly and comprehensively, whole and individual herbs of Banxia Xiexin decoction were analyzed by ultra-performance liquid chromatography with quadrupole-time-of-flight mass spectrometry (UPLC/Q-TOF-MS(E)). Under identical experiment conditions, chromatography results were compared between experiment groups. Based on the Q-TOF-MS(E) analysis, 74 peaks were identified on line. The herbal sources of these peaks were assigned. The results implied that flavonoids, triterpenoid saponins, alkaloids and glycosides were the main components in effective part of Banxia Xiexin decoction. The method established is simple and rapid for elucidation the constituents of Banxia Xiexin decoction and the results could be used for the quality control of Banxia Xiexin decoction.
Texto completo:
1
Base de dados:
WPRIM
Medicinas Tradicionais:
Medicinas_tradicionales_de_asia
/
Medicina_china
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Plantas Medicinais
/
Controle de Qualidade
/
Saponinas
/
Flavonoides
/
Medicamentos de Ervas Chinesas
/
Química
/
Cromatografia Líquida de Alta Pressão
/
Espectrometria de Massas por Ionização por Electrospray
/
Combinação de Medicamentos
/
Alcaloides
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2013
Tipo de documento:
Article