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Preventive and treatment effect of composite Rhodiolae on acute lung injury in patients with severe pulmonary hypertension during extracorporeal circulation / 中国中西医结合杂志
Article em Zh | WPRIM | ID: wpr-240897
Biblioteca responsável: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the possibility of early prevention and treatment of acute lung injury by using composite Rhodiolae (CR) in patients with severe pulmonary hypertension during extracorporeal circulation.</p><p><b>METHODS</b>Seventy-six patients with severe pulmonary hypertension screened out by color 2D-Doppler ultrasonography were randomly divided into the treated group (n = 40) and the control group (n = 36). The general treatment for the two groups, including preoperational preparation, operational procedure and conventional drug therapy, was the same. To the treated group, CR was administered 4 g every day (half the dose in children) at 7-10 day before and 5-7 day after the operation. The life signs, pulmonary ventilation parameters, arterial blood gas analysis were monitored and blood levels of TXB2, 6-keto-PGF1 alpha in both groups were determined in the fixed time points.</p><p><b>RESULTS</b>The various parameters in the treated group were all better than those in the control group (P < 0.05 or P < 0.01), the occurrence rate of acute lung injury and its mortality in the treated group were 7.5% (3/40) and 0% (0/3) respectively, while in the control group were 19.4% (7/36) and 43% (3/7) respectively.</p><p><b>CONCLUSION</b>CR has good preventive and treatment effect in treating complicated acute lung injury during extracorporeal circulation (cardiopulmonary bypass) in patients with pulmonary hypertension.</p>
Assuntos
Texto completo: 1 Base de dados: WPRIM Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia / Plantas_medicinales Assunto principal: Complicações Pós-Operatórias / Síndrome do Desconforto Respiratório / Cirurgia Geral / Medicamentos de Ervas Chinesas / Ponte Cardiopulmonar / Rhodiola / Usos Terapêuticos / Tratamento Farmacológico / Comunicação Interventricular / Hipertensão Pulmonar Idioma: Zh Revista: Chinese Journal of Integrated Traditional and Western Medicine Ano de publicação: 2003 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Medicinas Tradicionais: Medicinas_tradicionales_de_asia / Medicina_china Métodos Terapêuticos e Terapias MTCI: Terapias_biologicas / Aromoterapia / Plantas_medicinales Assunto principal: Complicações Pós-Operatórias / Síndrome do Desconforto Respiratório / Cirurgia Geral / Medicamentos de Ervas Chinesas / Ponte Cardiopulmonar / Rhodiola / Usos Terapêuticos / Tratamento Farmacológico / Comunicação Interventricular / Hipertensão Pulmonar Idioma: Zh Revista: Chinese Journal of Integrated Traditional and Western Medicine Ano de publicação: 2003 Tipo de documento: Article