Retrospective study on Xiaohe tablet-related liver damage and discussion on risk control / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2199-2203, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-262192
Biblioteca responsável:
WPRO
ABSTRACT
To investigate the clinical characteristics and risk factors of liver damage cases related to Xiaohe tablet so as to propose risk control measures. We search literatures on cases and group cases reports of Xiaohe tablet-related liver damage published domestically from 1978 to 2009, and then conduct a statistical analysis on the data. The 194 reports (9 cases reports and 185 group cases) of Xiaohe tablet-related liver damage are involved, the main clinical manifestations are gastrointestinal symptoms, skin stained yellow, icteric sclera, abnormal hepatic function and even hepatic failure. Most liver damage cases are reversible and can be cured by timely treatment after stopping use of this drug. There is a certain correlation between Xiaohe tablet and liver damage. Therefore, the following measures may be effective for risk control of Xiaohe tablet to use drug under the guidance of physician, according to the recommended dose and indications in drug specification; to closely monitor liver function during the clinical treatment; to strengthen safety-related basic study.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Medicinas Tradicionais:
Medicina Tradicional de Ásia
/
Medicina Chinesa
Assunto principal:
Patologia
/
Medicamentos de Ervas Chinesas
/
Estudos Retrospectivos
/
Doença Hepática Induzida por Substâncias e Drogas
/
Metabolismo
Tipo de estudo:
Estudo de etiologia
/
Guia de prática clínica
/
Estudo observacional
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2010
Tipo de documento:
Artigo
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