Therapeutic effects of sorafenib combined with transcatheter arterial chemoembolization and microwave ablation on postsurgical recurrent hepatocellular carcinoma / 中华肿瘤杂志
Chinese Journal of Oncology
; (12): 790-792, 2012.
Article
em Zh
| WPRIM
| ID: wpr-307293
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the therapeutic efficacy of sorafenib in combination with microwave coagulation therapy (MCT) and trans-arterial chemoembolization (TACE) in patients with recurrent liver cancer.</p><p><b>METHODS</b>From January 2006 to January 2010, 90 patients with recurrent hepatocellular carcinoma (HCC) were treated with MCT and TACE in our hospital. The treatment group received sorafenib + MCT + TACE, and the control group received MCT + TACE.</p><p><b>RESULTS</b>RR of the treatment group was 66.7%, which of the control group was 52.0% (P > 0.05). DCR was 83.3% in the treatment group and 64.5% in the control group (P < 0.05). Through a comparison of survival curves along with the extension of time, the survival rates of the two groups were decreased, but the treatment group (group 1) had a significantly higher one than the control group (group 2), with a statistically significant difference (P < 0.05).</p><p><b>CONCLUSION</b>Sorafenib combined with MCT and TACE can improve the disease control rate and prolong the survival in patients with recurrent HCC.</p>
Texto completo:
1
Base de dados:
WPRIM
Métodos Terapêuticos e Terapias MTCI:
Terapias_biologicas
Assunto principal:
Compostos de Fenilureia
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Cirurgia Geral
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Terapêutica
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Indução de Remissão
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Doxorrubicina
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Taxa de Sobrevida
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Seguimentos
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Carboplatina
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Quimioembolização Terapêutica
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Ablação por Cateter
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Idioma:
Zh
Revista:
Chinese Journal of Oncology
Ano de publicação:
2012
Tipo de documento:
Article