Mutagenicity Test for Hot Water Extract of Coix lacryma-jobi L. var. ma-yuen Stapf-Reverse Mutation Test, Mouse Lymphoma Assay (MLA) and Mouse Micronucleus Test / 日本補完代替医療学会誌

ABSTRACT

<i>Coix lacryma-jobi</i> L. <i>var. ma-yuen</i> Stapf is a grass long been used in traditional medicine as a nourishing food and reported to possess pharmacological effects including anti-tumor, anti-obesity, anti-diabetic, etc. In order to evaluate the possible mutagenicity of the hot water extract of all parts (husks, pellicles, and astringent skin) of the food, we performed a reverse mutation test in bacteria, a mouse lymphoma assay and a mouse micronucleus test. The results of all tests were negative. It was concluded that the extract has no mutagenicity for living bodies.<br>