COVID-19 Vaccine Hesitancy in Healthcare Workers and Attitude Changes During the Pandemic.

Objective: Many healthcare workers (HCWs) hesitated or refused to receive the COVID-19 vaccines during the pandemic. The attitudes of HCWs toward vaccines have an impact on society and patients. In this study, we aimed to investigate the reasons for vaccine hesitancy and refusal among HCWs during the COVID pandemic. Materials and Methods: We planned a two-step descriptive survey study. In the first step, we surveyed the unvaccinated HCWs in our hospital face-to-face after the first vaccination program. After eight months, we conducted another survey with the unvaccinated HCWs over the phone. We investigated the changes in their attitudes between the two surveys and the relationship of vaccine hesitation with their occupation and COVID-19 history. Results: After the first vaccine program, 325 (21.2%) HCWs out of 1532 did not get vaccinated in our hospital. We found that there was a significant relationship between vaccine hesitancy and occupation. In our study, the group of "non-HCWs" had the highest vaccine hesitancy rate at the beginning. The most common reasons for vaccine hesitancy were breastfeeding and pregnancy (29.5%) and side effects, especially allergic reactions (18.0%). After eight months, in the second survey, vaccine hesitancy dropped to 5.6%. We found that 80.1% of the HCWs who stated they were planning to get vaccinated in the first survey were vaccinated, and 62.4% of those who were not planning it were vaccinated. In the second survey, 1.8% of HCWs were still planning the vaccination, but 3.8% of HCWs refused the COVID-19 vaccine. Not believing in the efficacy of the vaccine in the first survey was associated with vaccine refusal in the second survey (p=0.001). Conclusion: The overall rate of vaccine refusal was low among HCWs. Nevertheless, vaccine refusal among HCWs having more information about the vaccine and disease than the community may be related to cultural, psychological, and political reasons other than efficacy and safety. Future studies on the cultural, psychological, and political reasons for vaccine refusal will contribute to understanding vaccine refusal and increasing vaccine acceptance.

Preliminary validation of the Turkish version of the pain catastrophizing scale for children and parents (PCS-C and PCS-P) in primary childhood headache.

OBJECTIVES: The aims of this study were to translate the pain catastrophizing scale for children and parents (PCS-C and PCS-P) into Turkish (TurPCS-C and TurPCS-P) and evaluate the psychometric properties in children with primary headache. METHODS: Exploratory factor analysis was used to test the construct validity. Reliability was measured using item-total score correlation, internal consistency (Cronbach α coefficient), Cronbach α if the item was deleted, and test-retest correlation. Concurrent validity and convergent validity of the scales were correlated with other scales (Revised Children's Anxiety and Depression Scale [RCADS], RCADS Parent RCADS-P, Quality of Life Scale for Children [PedsQL], and PedsQL-Parents [PedsQL-P]) and some related features (pain intensity, mobile phone usage time, and headache duration). RESULTS: Of the 80 children participating in the study, 55 (68.8%) were girls and 25 (31.2%) were boys. It was determined that the original three-factor structure was not supported for TurPCS-C and TurPCS-P. Cronbach α value was 0.871 for TurPCS-C consisting of 12 items, and Cronbach α value was 0.890 for TurPCS-P consisting of 12 items. As the PedsQL score increased, there was a negative correlation (p<0.05, r=-0.575) in all three areas of TurPCS-C, and there was a positive correlation (p<0.05) among the scores from the RCADS scale and TurPCS-C. Similarly, there was a negative correlation with PedsQL-P and TurPCS-P and positive correlation with RCADS-P and TurPCS-P (p<0.05 for each). CONCLUSION: TurPCS-C and TurPCS-P are an evaluation instrument with sufficient validity and reliability, and it can be reliably used to examine pediatric patients with primary headache.

An Evaluation of the Factors Related to Internet Gaming Disorder in Young Adults.

Background: Game addiction is a growing problem all over the world. The present study aimed to evaluate the prevalence and psychological, social, and behavioral effects of internet gaming disorder (IGD) on young adults. Methods: A preliminary study was conducted and the game types most commonly played on the internet were determined. Then, approximately 60 gaming site managers were contacted. After obtaining consent, the questionnaires were sent to gaming site members and they were asked to complete the questionnaires. Data were collected through a sociodemographic form, Internet Gaming Disorder Scale-Short Form (IGDS9-SF), Strengths and Difficulties Questionnaire (SDQ), and State-Trait Anxiety Inventory (STAI). Findings: The study was conducted with 613 participants. The age of the participants ranged from 15 to 30 years, with a mean age of 20.80±4.63 years. The prevalence of IGD was 10% (n=67). Those with low-income families and low academic performance were identified as more likely to develop IGD. Moreover, IGD was revealed to be more likely in individuals with fewer close friends, playing games from an early age, and those with a habit of devoting extensive time to watching online game videos on Twitch or YouTube. In addition, the risk of gaming disorder was approximately two times higher in individuals who preferred First Person Shooter (FPS) games and Massively Multiplayer Online Role-Playing Games (MMORPG). Conclusion: The results of this study could be useful for estimating the level of IGD and carrying out more comprehensive studies to possibly be able to control IGD.

Is There a Gender Difference in Terms of Inflammatory Biomarkers in Patients With Severe Covid-19 Pneumonia?

Background The men infected with COVID-19 have been shown to have more severe disease and a higher mortality rate. Morbidity and mortality associated with COVID-19 are mediated through intense viral inflammation and increased levels of inflammatory biomarkers. We aimed to retrospectively evaluate any gender difference in patients with severe COVID-19 pneumonia in terms of inflammatory biomarkers. Methods Our study included 132 patients. The general characteristics, radiological features and laboratory parameters of the patients were recorded. Results No difference was observed between the genders according to comorbidities, pulse steroid requirement and hypoxemia. There was no difference between the male and female participants in terms of age, white blood cell count, lymphocyte count, red cell distribution width, C-reactive protein, troponin, albumin and D-dimer. However, duration of hospitalization; percentage of polymorphonuclear leukocyte (PNL); and haemoglobin, alanine aminotransferase and ferritin values were higher in the males, and lymphocyte percentage and platelet count were higher in the women participants. Conclusion Larger studies with gender-specific reporting and robust analyses are required to clarify how gender alters the cellular and molecular pathways associated with COVID-19. This would improve the interpretation of biomarkers and the clinical management of COVID-19 patients by facilitating a personalised medical approach to risk stratification, prevention and treatment.

Effectiveness of anti-smoking interventions towards community: a meta-analysis study.

OBJECTIVES: Smoking is one of the biggest public health problems in the world. The World Health Organization (WHO) has declared the MPOWER package which provides a guide for tobacco control. The package includes six evidence based anti-smoking interventions. This meta-analysis study aims to assess the effectiveness of MPOWER - (M)onitor, (P)rotect, (O)ffer, (W)arn, (E)nforce, and (R)aise. In the study, "smoking prevalence rate, smoking cessation rate and number of cigarettes smoked daily" outputs were used in adult and adolescent age groups. METHODS: Literature search has been made with "smok*, tobacco, cigarette*" keywords from the databases of Medline, Web of Science, Scopus, and Cochrane-Library. Abstracts were assessed in detail according to the inclusion criteria by the research team. Quality of articles was evaluated with modified Jadad criteria. The follow-up periods of articles were determined in two groups named as short and long term periods. We used random effects model (p ≤ 0.05) and fixed effects model (p > 0.05) according to the heterogeneity test results. RESULTS: P and O interventions, which are evaluated with smoking cessation rate, increased the smoking cessation rate in adults by 39% in the longest follow-up period - RR: 1.39 (1.23-1.57). However, it was determined that the interventions were not effective on smoking cessation rate in adolescents - RR: 1.13 (0.90-1.42). Nicotine replacement therapy (NRT) was the most effective intervention for smoking cessation rate in adults. W interventions, which are evaluated with smoking prevalence rate, decreased the smoking prevalence rate in adults by 13% in the longest follow-up period - OR: 0.87 (0.82-0.92). P, W and E interventions, which are evaluated with smoking prevalence rate, decreased the smoking prevalence rate in adolescents by 26% in the longest follow-up period - OR: 0.74 (0.68-0.80). CONCLUSIONS: MPOWER interventions affect smoking prevalence rate, smoking cessation rate and number of cigarettes smoked daily in different age groups. Well-controlled, well-planned and cost-effective anti-smoking interventions have great importance for public health protection.

Cross-cultural adaptation, reliability, and validity of the Turkish version of the obesity-specific quality of life questionnaire: quality of life, obesity, and dietetics (QOLOD) rating scale

Background/aim: Obesity is one of the main public health issues in many countries including Turkey. The aim of the study is to test cross-cultural adaptation, reliability, and validity of QOLOD rating scale in the Turkish language. Materials and methods: This methodological study was conducted among the overweight and obesity people between February-March, 2018 in Ankara Atatürk Training and Research Hospital. The data was collected through self-report and face to face interviews. The QOLOD rating scale has 36 items, a 5-point Likert scale (1­5) is used for each question. Results: In the study, of the 180 participants, 101 (56.1%) were female, 79 (43.9%) were male, and the mean age was 43.36 ± 14.28 (min-max 18­87) years. According to the CFA, the Turkish version of QOLOD rating scale shows a multidimensional structure consisting of 34 items. Two items (item 11 and item 35) were excluded from the scale according to the CFA. Cronbach's Alpha value changes between 0.927­0.930. Conclusion: Finding shows that the Turkish version of QOLOD rating scale had sufficient validity and reliability for Turkish population, had strong psychometric characteristics.

Violence and related factors among high school students in semirural areas of Eskisehir.

OBJECTIVE: The aim of the study was to determine the frequency of violence-related behaviors and related factors at school or school environment among high school students educated in the semirural areas of Eskisehir. METHODS: This was a cross-sectional study. The sample comprised 1465 high school students. Data were collected using a questionnaire that included questions regarding sociodemographic characteristics and the 2013 survey questions of the "Youth Risk Behavior Surveillance System" of the Centers for Disease Control and Prevention. RESULTS: It was found that 8.5% of students exhibited violent behaviors at school or school environment. According to multiple logistic regression analysis, sex, father's employment status, smoking, alcohol use, and feeling unsafe were effective independent variables on violence. CONCLUSION: Students had a high rate of violence-related behaviors at school or school environment. Community-based public health interventions are required to solve this problem.