RESUMEN
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been reported to trigger several autoimmune diseases. There are also recent reports of autoimmune diseases that develop after SARS-CoV-2 vaccines. Autoimmune hepatitis is a polygenic multifactorial disease, which is diagnosed using a scoring system. A 61-year-old woman presented with malaise, fatigue, loss of appetite, nausea and yellow eyes. She had a Pfizer/BioNTech BNT162b2 mRNA vaccine a month ago. Her physical examination revealed jaundice all over the body, especially in the sclera. The laboratory tests showed elevated liver enzymes and bilirubin levels. Antinuclear antibody and anti-smooth muscle antibody were positive and immunoglobulin G was markedly elevated. The liver biopsy revealed histopathological findings consistent with autoimmune hepatitis (AIH). The patient was diagnosed with AIH and initiated on steroid therapy. She rapidly responded to steroid therapy. A few cases of AIH have been reported after the COVID-19 vaccine so far. Although the exact cause of autoimmune reactions is unknown, an abnormal immune response and bystander activation induced by molecular mimicry is considered a potential mechanism, especially in susceptible individuals. As intensive vaccination against SARS-CoV-2 continues, we would like to emphasize that clinicians should be cautious and consider AIH in patients presenting with similar signs and symptoms.
Asunto(s)
Vacuna BNT162 , COVID-19 , Hepatitis Autoinmune , Femenino , Enfermedad de Hashimoto/complicaciones , Humanos , Persona de Mediana Edad , SARS-CoV-2RESUMEN
Kimura disease (KD) is a rare entity that occurs primarily in Asian people characterized histopathologically by a lymph-folliculoid granuloma with infiltration of the mass and the surrounding tissues by eosinophils, often with concomitant peripheral blood eosinophilia and elevated serum immunoglobulin E, generally seen in the head and neck region, especially preauricular area. In this article, we present the case of a 14-year-old male patient with KD on his left parotid area. The clinical, radiologic, surgical, and pathologic findings of KD are discussed in this article.
Asunto(s)
Hiperplasia Angiolinfoide con Eosinofilia/diagnóstico , Hiperplasia Angiolinfoide con Eosinofilia/cirugía , Enfermedades de las Parótidas/diagnóstico , Enfermedades de las Parótidas/cirugía , Adolescente , Hiperplasia Angiolinfoide con Eosinofilia/patología , Medios de Contraste , Diagnóstico Diferencial , Humanos , Imagen por Resonancia Magnética , Masculino , Enfermedades de las Parótidas/patologíaRESUMEN
The hydatid cyst of the adrenal gland is extremely rare pathology of the adrenal gland; here we report an adrenal hydatid cyst that presented as a solitary renal tumor.
Asunto(s)
Enfermedades de las Glándulas Suprarrenales/parasitología , Equinococosis , Enfermedades de las Glándulas Suprarrenales/diagnóstico , Enfermedades de las Glándulas Suprarrenales/diagnóstico por imagen , Enfermedades de las Glándulas Suprarrenales/tratamiento farmacológico , Antinematodos/uso terapéutico , Equinococosis/diagnóstico , Equinococosis/diagnóstico por imagen , Equinococosis/tratamiento farmacológico , Femenino , Humanos , Mebendazol/uso terapéutico , Persona de Mediana Edad , Tomografía Computarizada por Rayos XRESUMEN
Infantile myofibromatosis presents as a firm, nodular mass in soft tissues, muscles, or visceras which can be solitary or multicentric, and it may regress spontaneously. We present a one-day-old boy who was admitted to the hospital for two masses, with one below the umbilicus that looked like a hemangiomatous structure and the other in the abdominal skin as a subcutaneous nodule. There was no intraabdominal involvement, and both of the masses were resected at 10 days of life. The one-year follow-up was uneventful.