RESUMEN
We have investigated the biocompatibility of calcium phosphate coatings deposited by pulsed laser ablation from hydroxyapatite (HA) targets onto polyethylene and Teflon substrates. It was found that the cell density, attachment, and morphology of primary rat calvaria osteoblasts were influenced by both the original polymer and by the nature of the apatite coatings. HA coatings on Teflon were found to have higher biocompatibility in terms of cell adhesion and spreading. In vivo studies of bone response to coatings deposited by KrF excimer and CO2 lasers on commercial Ti6A14V alloy implants show that both deposition techniques suppress fibrous tissue formation and promote osteogenesis. © 1998 Society of Photo-Optical Instrumentation Engineers.
RESUMEN
Use of various lasers and regimens for spraying the coatings and for additional thermal processing makes it possible to purposefully alter the morphology, composition, and crystallinity of the coatings, and hence, the optimal coatings, as regards their biological activity, may be created. Replacement of eximer lasers with CO2 lasers makes the spraying process cheaper and comparable in efficacy with the plasma process, with the quality of coatings and reproducibility of their parameters appreciably improved. Experiments with coatings of three types, sprayed by CO2 lasers, demonstrated that they met the mechanical and physico-chemical requirements of biocompatibility.
Asunto(s)
Materiales Biocompatibles/efectos de la radiación , Implantes Dentales , Rayos Láser , Materiales Biocompatibles/química , Durapatita/química , Durapatita/efectos de la radiación , Análisis de Fourier , Microscopía Electrónica de Rastreo , Espectrofotometría Infrarroja , Propiedades de Superficie , Tecnología Odontológica/métodos , Temperatura , VacioRESUMEN
Rat experiments were performed to study osteogenesis and osseointegration in implanting fragments of dental titanic implants into the spongy bone. The implant spray-coating with hydroxyapatite produced by excimer and CO2 lasers stimulates osteogenesis. Bone tissue integration with implant proceeds more actively in response to CO2 laser radiation. The weakest integration was registered between the metal and bone tissues.